Bcl-xL DNAzymes promote radiosensitivity and chemosensitivity in colorectal cancer cells via enhancing apoptosis

• मुख्य लेखकों: Zhen Yu (लेखक), Jun Guo (लेखक), Tao Meng (लेखक), Lei Ge (लेखक), Lin Liu (लेखक), Haijiang Wang (लेखक), Xinhui Yang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2022-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background RNA-cleaving deoxyribozymes (DNAzymes) are catalytic deoxyribonucleic acid molecules that have become a promising new class of gene suppressors by binding and cleaving target mRNA. This study investigated whether DNAzymes targeting Bcl-xL enhanced the effectiveness of radiotherap...