Origami of KR-12 Designed Antimicrobial Peptides and Their Potential Applications

• Main Authors: Jayaram Lakshmaiah Narayana (Author), Abraham Fikru Mechesso (Author), Imran Ibni Gani Rather (Author), D. Zarena (Author), Jinghui Luo (Author), Jingwei Xie (Author), Guangshun Wang (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This review describes the discovery, structure, activity, engineered constructs, and applications of KR-12, the smallest antibacterial peptide of human cathelicidin LL-37, the production of which can be induced under sunlight or by vitamin D. It is a moonlighting peptide that shows both antimicrobia...