Variable glucagon metabolic actions in diverse mouse models of obesity and type 2 diabetes

• Main Authors: Yuqin Wu (Author), Andrea Y. Chan (Author), Jana Hauke (Author), Okka Htin Aung (Author), Ashish Foollee (Author), Maria Almira S. Cleofe (Author), Helen Stölting (Author), Mei-Ling Han (Author), Katherine J. Jeppe (Author), Christopher K. Barlow (Author), Jürgen G. Okun (Author), Patricia M. Rusu (Author), Adam J. Rose (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The study aimed to investigate the effects of glucagon on metabolic pathways in mouse models of obesity, fatty liver disease, and type 2 diabetes (T2D) to determine the extent and variability of hepatic glucagon resistance in these conditions. Methods: We investigated glucagon's effe...