Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

• Главные авторы: Janne R. Hingst (Автор), Rasmus Kjøbsted (Автор), Jesper B. Birk (Автор), Nicolas O. Jørgensen (Автор), Magnus R. Larsen (Автор), Kohei Kido (Автор), Jeppe Kjærgaard Larsen (Автор), Sasha A.S. Kjeldsen (Автор), Joachim Fentz (Автор), Christian Frøsig (Автор), Stephanie Holm (Автор), Andreas M. Fritzen (Автор), Tine L. Dohlmann (Автор), Steen Larsen (Автор), Marc Foretz (Автор), Benoit Viollet (Автор), Peter Schjerling (Автор), Peter Overby (Автор), Jens F. Halling (Автор), Henriette Pilegaard (Автор), Ylva Hellsten (Автор), Jørgen F.P. Wojtaszewski (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2020-10-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Objective: Evidence for AMP-activated protein kinase (AMPK)-mediated regulation of skeletal muscle metabolism during exercise is mainly based on transgenic mouse models with chronic (lifelong) disruption of AMPK function. Findings based on such models are potentially biased by secondary effects rela...