In celebration of a century with insulin - Update of insulin gene mutations in diabetes

• Main Authors: Julie Støy (Author), Elisa De Franco (Author), Honggang Ye (Author), Soo-Young Park (Author), Graeme I. Bell (Author), Andrew T. Hattersley (Author)
• Format: Book
• Published: Elsevier, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: While insulin has been central to the pathophysiology and treatment of patients with diabetes for the last 100 years, it has only been since 2007 that genetic variation in the INS gene has been recognised as a major cause of monogenic diabetes. Both dominant and recessive mutations in th...