Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites

• Autors principals: Sisi Kang (Autor), Mei Yang (Autor), Zhongsi Hong (Autor), Liping Zhang (Autor), Zhaoxia Huang (Autor), Xiaoxue Chen (Autor), Suhua He (Autor), Ziliang Zhou (Autor), Zhechong Zhou (Autor), Qiuyue Chen (Autor), Yan Yan (Autor), Changsheng Zhang (Autor), Hong Shan (Autor), Shoudeng Chen (Autor)
• Format: Llibre
• Publicat: Elsevier, 2020-07-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 virus continually lead to worldwide human infections and deaths. Currently, there is no specific viral protein-targeted therapeutics. Viral nucleocapsid protein is a potential antiviral drug target, serving multiple critical functio...