Induction of Apoptosis by Isoalantolactone in Human Hepatocellular Carcinoma Hep3B Cells through Activation of the ROS-Dependent JNK Signaling Pathway

• Main Authors: Min Yeong Kim (Author), Hyesook Lee (Author), Seon Yeong Ji (Author), So Young Kim (Author), Hyun Hwangbo (Author), Shin-Hyung Park (Author), Gi-Young Kim (Author), Cheol Park (Author), Sun-Hee Leem (Author), Su Hyun Hong (Author), Yung Hyun Choi (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Isoalantolactone (IALT) is one of the isomeric sesquiterpene lactones isolated from the roots of <i>Inula helenium</i> L. IALT is known to possess various biological and pharmacological activities, but its anti-cancer mechanisms are not well understood. The aim of the present study was t...