Morinda citrifolia Linn. Reduces Parasite Load and Modulates Cytokines and Extracellular Matrix Proteins in C57BL/6 Mice Infected with Leishmania (Leishmania) amazonensis.

• Main Authors: Fernando Almeida-Souza (Author), Flávia de Oliveira Cardoso (Author), Bruno Vinicius da Conceição Souza (Author), Tânia Zaverucha do Valle (Author), Joicy Cortez de Sá (Author), Iara Dos Santos da Silva Oliveira (Author), Celeste da Silva Freitas de Souza (Author), Carla Junqueira Moragas Tellis (Author), Maria do Socorro Dos Santos Chagas (Author), Maria Dutra Behrens (Author), Ana Lúcia Abreu-Silva (Author), Kátia da Silva Calabrese (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The absence of an effective vaccine and the debilitating chemotherapy for Leishmaniasis demonstrate the need for developing alternative treatments. Several studies conducted with Morinda citrifolia have shown various biological activities, including antileishmanial activity, however its mechanisms o...