Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia

• Main Authors: Jayna J Mistry (Author), Charlotte Hellmich (Author), Amelia Lambert (Author), Jamie A Moore (Author), Aisha Jibril (Author), Angela Collins (Author), Kristian M Bowles (Author), Stuart A Rushworth (Author)
• Format: Book
• Published: BMC, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Acute myeloid leukemia (AML) remains an incurable malignancy despite recent advances in treatment. Recently a number of new therapies have emerged for the treatment of AML which target BCL-2 or the membrane receptor CD38. Here, we show that treatment with Venetoclax and Daratumumab combinat...