Vitamin D and the Epithelial to Mesenchymal Transition

• Hauptverfasser: María Jesús Larriba (Verfasst von), Antonio García de Herreros (Verfasst von), Alberto Muñoz (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2016-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Several studies support reciprocal regulation between the active vitamin D derivative 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) and the epithelial to mesenchymal transition (EMT). Thus, 1,25(OH)2D3 inhibits EMT via the induction of a variety of target genes that encode cell adhesion and polarity prote...