Loss of Pten in renal tubular cells leads to water retention by upregulating AQP2

• Main Authors: Zhuo Sun (Author), Xiaotong Shao (Author), Haotian Wu (Author), Yaxian Zhao (Author), Yidan Cao (Author), Danhua Li (Author), Ying Sun (Author), Qingling Wang (Author)
• Format: Book
• Published: Karger Publishers, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Phosphatase and tensin (PTEN) is a multifunctional gene associated with the normal development and physiological function of various tissues including the kidney. However, its role in renal tubular reabsorption function has not been well elucidated. Methods: We generated a renal tubule...