Analysis of multiple gene co-expression networks to discover interactions favoring CFTR biogenesis and ΔF508-CFTR rescue

Abstract Background We previously reported that expression of a miR-138 mimic or knockdown of SIN3A in primary cultures of cystic fibrosis (CF) airway epithelia increased ΔF508-CFTR mRNA and protein levels, and partially restored CFTR-dependent chloride transport. Global mRNA transcript profiling in...

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Main Authors: Matthew D. Strub (Author), Long Gao (Author), Kai Tan (Author), Paul B. McCray (Author)
Format: Book
Published: BMC, 2021-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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