A novel method based on unbiased correlations tests for covariate selection in nonlinear mixed effects models: The COSSAC approach

Abstract Building a covariate model is a crucial task in population pharmacokinetics and pharmacodynamics in order to understand the determinants of the interindividual variability. Identifying a good covariate model usually requires many runs. Several procedures have been proposed in the past to au...

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Main Authors: Géraldine Ayral (Author), Jean‐François Si Abdallah (Author), Claude Magnard (Author), Jonathan Chauvin (Author)
Format: Book
Published: Wiley, 2021-04-01T00:00:00Z.
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3rd Floor Main Library

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