Osteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted Therapies

• Main Authors: Ander Abarrategi (Author), Juan Tornin (Author), Lucia Martinez-Cruzado (Author), Ashley Hamilton (Author), Enrique Martinez-Campos (Author), Juan P. Rodrigo (Author), M. Victoria González (Author), Nicola Baldini (Author), Javier Garcia-Castro (Author), Rene Rodriguez (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteosarcoma (OS) is the most common type of primary solid tumor that develops in bone. Although standard chemotherapy has significantly improved long-term survival over the past few decades, the outcome for those patients with metastatic or recurrent OS remains dismally poor and, therefore, novel a...