Current LC-MS-based strategies for characterization and quantification of antibody-drug conjugates

• Những tác giả chính: Xiaoyu Zhu (Tác giả), Shihan Huo (Tác giả), Chao Xue (Tác giả), Bo An (Tác giả), Jun Qu (Tác giả)
• Định dạng: Sách
• Được phát hành: Elsevier, 2020-06-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

The past few years have witnessed enormous progresses in the development of antibody-drug conjugates (ADCs). Consequently, comprehensive analysis of ADCs in biological systems is critical in supporting discovery, development and evaluation of these agents. Liquid chromatography-mass spectrometry (LC...