Tissue factor (coagulation factor III): a potential double-edge molecule to be targeted and re-targeted toward cancer

• Main Authors: Seyed Esmaeil Ahmadi (Author), Ashkan Shabannezhad (Author), Amir Kahrizi (Author), Armin Akbar (Author), Seyed Mehrab Safdari (Author), Taraneh Hoseinnezhad (Author), Mohammad Zahedi (Author), Soroush Sadeghi (Author), Mahsa Golizadeh Mojarrad (Author), Majid Safa (Author)
• Format: Book
• Published: BMC, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Tissue factor (TF) is a protein that plays a critical role in blood clotting, but recent research has also shown its involvement in cancer development and progression. Herein, we provide an overview of the structure of TF and its involvement in signaling pathways that promote cancer cell pr...