Peroxisomal Fatty Acid Oxidation and Glycolysis Are Triggered in Mouse Models of Lesional Atopic Dermatitis

• Main Authors: Petra Pavel (Author), Géraldine Leman (Author), Martin Hermann (Author), Christian Ploner (Author), Thomas O. Eichmann (Author), Deborah Minzaghi (Author), Franz P.W. Radner (Author), Barbara Del Frari (Author), Robert Gruber (Author), Sandrine Dubrac (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alterations of the lipid profile of the stratum corneum have an important role in the pathogenesis of atopic dermatitis (AD) because they contribute to epidermal barrier impairment. However, they have not previously been envisioned as a cellular response to altered metabolic requirements in AD epide...