Hypoxia-induced circSTT3A enhances serine synthesis and promotes H3K4me3 modification to facilitate breast cancer stem cell formation

• Main Authors: Ming Xu (Author), Xiaoqi Liu (Author), Xinyue Zhou (Author), Yilu Qin (Author), Liping Yang (Author), Siyang Wen (Author), Yuxiang Qiu (Author), Shanchun Chen (Author), Rui Tang (Author), Yuetong Guo (Author), Manran Liu (Author), Yan Sun (Author)
• Format: Book
• Published: Elsevier, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypoxia is a key feature of tumor microenvironment that contributes to the development of breast cancer stem cells (BCSCs) with strong self-renewal properties. However, the specific mechanism underlying hypoxia in BCSC induction is not completely understood. Herein, we provide evidence that a novel...