Formulation and Evaluation of Prednisolone Sodium Metazoate-Loaded Mucoadhesive Quatsomal Gel for Local Treatment of Recurrent Aphthous Ulcers: Optimization, In Vitro, Ex Vivo, and In Vivo Studies

• Main Authors: Ashraf Kassem (Author), Hanan Refai (Author), Mohamed A. El-Nabarawi (Author), Menna M. Abdellatif (Author)
• 格式: 圖書
• 出版: MDPI AG, 2023-07-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

This study aims to formulate a buccal mucoadhesive gel containing prednisolone sodium metazoate-loaded quatsomes for efficient localized therapy of recurrent aphthous ulcers. Quatsomes were prepared using a varied concentration of quaternary ammonium surfactants (QAS) and cholesterol (CHO). A 2<s...