Formulation and evaluation of sustained release matrix tablet of rabeprazole using wet granulation technique

• Main Authors: Ruqaiyah Khan (Author), Md Shamim Ashraf (Author), Muhammad Afzal (Author), Imran Kazmi (Author), Mohammed Asadullah Jahangir (Author), Rajbala Singh (Author), Ramesh Chandra (Author), Firoz Anwar (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Rabeprazole, a member of substituted benzimidazoles, inhibits the final step in gastric acid secretions. This drug claims to cause fastest acid separation (due to higher pKa), and more rapidly converts to the active species to aid gastric mucin synthesis. The most significant pharmacol...