PKD2 mutation in an Iranian autosomal dominant polycystic kidney disease family with misleading linkage analysis data

• Main Authors: Mona Entezam (Author), Mohammad Reza Khatami (Author), Fereshteh Saddadi (Author), Mohsen Ayati (Author), Jamshid Roozbeh (Author), Mohammad Keramatipour (Author)
• Format: Book
• Published: The Korean Society of Nephrology, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic renal disorder caused by mutation in 2 genes PKD1 and PKD2. Thus far, no mutation is identified in approximately 10% of ADPKD families, which can suggest further locus heterogeneity. Owing to the complexity o...