PKD2 mutation in an Iranian autosomal dominant polycystic kidney disease family with misleading linkage analysis data

• Những tác giả chính: Mona Entezam (Tác giả), Mohammad Reza Khatami (Tác giả), Fereshteh Saddadi (Tác giả), Mohsen Ayati (Tác giả), Jamshid Roozbeh (Tác giả), Mohammad Keramatipour (Tác giả)
• Định dạng: Sách
• Được phát hành: The Korean Society of Nephrology, 2016-06-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic renal disorder caused by mutation in 2 genes PKD1 and PKD2. Thus far, no mutation is identified in approximately 10% of ADPKD families, which can suggest further locus heterogeneity. Owing to the complexity o...