Sulphonamide inhibition studies of the β-carbonic anhydrase GsaCAβ present in the salmon platyhelminth parasite Gyrodactylus salaris

• Hauptverfasser: Ashok Aspatwar (VerfasserIn), Alessandro Bonardi (VerfasserIn), Heidi Aisala (VerfasserIn), Ksenia Zueva (VerfasserIn), Craig R Primmer (VerfasserIn), Jaakko Lumme (VerfasserIn), Seppo Parkkila (VerfasserIn), Claudiu T. Supuran (VerfasserIn)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Schlagworte: article
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A β-class carbonic anhydrase (CA, EC 4.2.1.1) present in the genome of the Monogenean platyhelminth Gyrodactylus salaris, a fish parasite, GsaCAβ, has been investigated for its inhibitory effects with a panel of sulphonamides and sulfamates, some of which in clinical use. Several effective GsaCAβ in...