The clinical effectiveness and cost effectiveness of clozapine for inpatients with severe borderline personality disorder (CALMED study): a randomised placebo-controlled trial

• Main Authors: Mike J. Crawford (Author), Verity C. Leeson (Author), Rachel Evans (Author), Barbara Barrett (Author), Aisling McQuaid (Author), Jack Cheshire (Author), Rahil Sanatinia (Author), Gary Lamph (Author), Piyal Sen (Author), Katina Anagnostakis (Author), Louise Millard (Author), Inti Qurashi (Author), Fintan Larkin (Author), Nusrat Husain (Author), Paul Moran (Author), Thomas R.E. Barnes (Author), Carol Paton (Author), Zoe Hoare (Author), Marco Picchioni (Author), Simon Gibbon (Author)
• Format: Book
• Published: SAGE Publishing, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Data from case series suggest that clozapine may benefit inpatients with borderline personality disorder (BPD), but randomised trials have not been conducted. Methods: Multicentre, double-blind, placebo-controlled trial. We aimed to recruit 222 inpatients with severe BPD aged 18 or over,...