Tokishakuyakusan ameliorates spatial memory deficits induced by ovariectomy combined with β-amyloid in rats

• Main Authors: Nobuaki Egashira (Author), Yuki Akiyoshi (Author), Hikari Iba (Author), Takashi Arai (Author), Izzettin Hatip- (Author), Kenichi Mishima (Author), Katsunori Iwasaki (Author)
• Format: Book
• Published: Elsevier, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previously, we reported that ovariectomy (OVX) combined with β-amyloid peptide (Aβ) impaired spatial memory by decreasing extracellular acetylcholine (ACh) levels in the dorsal hippocampus. Here, we investigated the effect of tokishakuyakusan (TSS), a Kampo medicine, on the impairment of spatial mem...