Protective Effect of Knee Postoperative Fluid on Oxidative-Induced Damage in Human Knee Articular Chondrocytes

• Үндсэн зохиолчид: Roberta Giordo (Зохиогч), Smitha Tulasigeri Totiger (Зохиогч), Gianfilippo Caggiari (Зохиогч), Annalisa Cossu (Зохиогч), Andrea Fabio Manunta (Зохиогч), Anna Maria Posadino (Зохиогч), Gianfranco Pintus (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2024-02-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The oxidative-stress-elicited deterioration of chondrocyte function is the initial stage of changes leading to the disruption of cartilage homeostasis. These changes entail a series of catabolic damages mediated by proinflammatory cytokines, MMPs, and aggrecanases, which increase ROS generation. Suc...