Placental OPRM1 DNA methylation and associations with neonatal opioid withdrawal syndrome, a pilot study

• Main Authors: Elisha M. Wachman (Author), Alice Wang (Author), Breanna C. Isley (Author), Jeffery Boateng (Author), Jacob A. Beierle (Author), Aaron Hansbury (Author), Hira Shrestha (Author), Camron Bryant (Author), Huiping Zhang (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Epigenetic variation of DNA methylation of the mu-opioid receptor gene (OPRM1) has been identified in the blood and saliva of individuals with opioid use disorder (OUD) and infants with neonatal opioid withdrawal syndrome (NOWS). It is unknown whether epigenetic variation in OPRM1 exists within...