A Mycobacterial Perspective on Tuberculosis in West Africa: Significant Geographical Variation of M. africanum and Other M. tuberculosis Complex Lineages.

• Main Authors: Florian Gehre (Author), Samrat Kumar (Author), Lindsay Kendall (Author), Mebrat Ejo (Author), Oumie Secka (Author), Boatema Ofori-Anyinam (Author), Emmanuel Abatih (Author), Martin Antonio (Author), Dirk Berkvens (Author), Bouke C de Jong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Phylogenetically distinct Mycobacterium tuberculosis lineages differ in their phenotypes and pathogenicity. Consequently, understanding mycobacterial population structures phylogeographically is essential for design, interpretation and generalizability of clinical trials. Comprehensive ef...