Mutational landscape of nasopharyngeal carcinoma based on targeted next-generation sequencing: implications for predicting clinical outcomes

• Main Authors: Zihan Zhou (Author), Peifeng Li (Author), Xianbin Zhang (Author), Juan Xu (Author), Jin Xu (Author), Shui Yu (Author), Dongqing Wang (Author), Wei Dong (Author), Xiujuan Cao (Author), Hongjiang Yan (Author), Mingping Sun (Author), Xiuping Ding (Author), Jun Xing (Author), Peng Zhang (Author), Limin Zhai (Author), Tingyong Fan (Author), Shiyu Tian (Author), Xinhua Yang (Author), Man Hu (Author)
• Format: Book
• Published: BMC, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The aim of this study was to draw a comprehensive mutational landscape of nasopharyngeal carcinoma (NPC) tumors and identify the prognostic factors for distant metastasis-free survival (DMFS). Methods A total of forty primary nonkeratinizing NPC patients underwent targeted next-g...