Influenza A Virus-Driven Airway Inflammation may be Dissociated From Limb Muscle Atrophy in Cigarette Smoke-Exposed Mice

• Main Authors: Kevin Mou (Author), Stanley M. H. Chan (Author), Kurt Brassington (Author), Aleksandar Dobric (Author), Simone N. De Luca (Author), Huei Jiunn Seow (Author), Stavros Selemidis (Author), Steven Bozinovski (Author), Ross Vlahos (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Limb muscle dysfunction is a hallmark of Chronic Obstructive Pulmonary Disease (COPD) which is further worsened following a viral-induced acute exacerbation of COPD (AECOPD). An amplified airway inflammation underlies the aggravated respiratory symptoms seen during AECOPD, however, its contributory...