Comparative Stability Study of Polysorbate 20 and Polysorbate 80 Related to Oxidative Degradation

The surfactants polysorbate 20 (PS20) and polysorbate 80 (PS80) are utilized to stabilize protein drugs. However, concerns have been raised regarding the degradation of PSs in biologics and the potential impact on product quality. Oxidation has been identified as a prevalent degradation mechanism un...

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Main Authors: Benedykt Kozuch (Author), Johanna Weber (Author), Julia Buske (Author), Karsten Mäder (Author), Patrick Garidel (Author), Tim Diederichs (Author)
Format: Book
Published: MDPI AG, 2023-09-01T00:00:00Z.
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3rd Floor Main Library

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