Model‐based meta‐analysis using latent variable modeling to set benchmarks for new treatments of systemic lupus erythematosus

• Main Authors: Kosalaram Goteti (Author), Ramon Garcia (Author), William R. Gillespie (Author), Jonathan French (Author), Lena Klopp‐Schulze (Author), Ying Li (Author), Cristina Vazquez Mateo (Author), Sanjeev Roy (Author), Oliver Guenther (Author), Lisa Benincosa (Author), Karthik Venkatakrishnan (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Several investigational agents are under evaluation in systemic lupus erythematosus (SLE) clinical trials but quantitative frameworks to enable comparison of their efficacy to reference benchmark treatments are lacking. To benchmark SLE treatment effects and identify clinically important co...