Evaluation of Serum/Urine Genomic and Metabolomic Profiles to Improve the Adherence to Sildenafil Therapy in Patients with Erectile Dysfunction

• Main Authors: Maria Santa Rocca (Author), Alessia Vignoli (Author), Leonardo Tenori (Author), Marco Ghezzi (Author), Maurizio De Rocco Ponce (Author), Giannis Vatsellas (Author), Dimitris Thanos (Author), Roberto Padrini (Author), Carlo Foresta (Author), Luca De Toni (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Type V-phosphodiesterase-inhibitors (PDE5i) are the first choice drugs in the treatment of erectile dysfunction (ED), being effective in 60-70% of patients. However, approximately 50% of patients per year discontinue the treatment with PDE5i after reporting poor drug efficacy or major adverse drug r...