Inhibition of Osteoclast Generation: A Novel Function of the Bone Morphogenetic Protein 7/Osteogenic Protein 1

• Główni autorzy: Thomas Maurer (Autor), Gerald Zimmermann (Autor), Susanne Maurer (Autor), Sabine Stegmaier (Autor), Christof Wagner (Autor), G. Maria Hänsch (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2012-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Monocytes have the potential to differentiate to either macrophages, dendritic cells, or to osteoclasts. The microenvironment, particularly cytokines, directs the monocyte differentiation. Receptors of NFκB (RANK) ligand, tumor necrosis factor (TNF) α, or interleukin- (IL-) 8 have be identified as i...