Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug
Metoprolol is used for phenotyping of cytochrome P450 (CYP) 2D6, a CYP isoform considered not to be inducible by inducers of the CYP2C, CYP2B, and CYP3A families such as rifampicin. While assessing CYP2D6 activity under basal conditions and after pre-treatment with rifampicin in vivo, we surprisingl...
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| Main Authors: | , , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2018-07-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |