Neuroprotective Effects of Quercetin and Rutin on Spatial Memory Impairment in an 8-Arm Radial Maze Task and Neuronal Death Induced by Repeated Cerebral Ischemia in Rats

• Main Authors: Fengling Pu (Author), Kenichi Mishima (Author), Keiichi Irie (Author), Kyouko Motohashi (Author), Yurika Tanaka (Author), Kensuke Orito (Author), Takashi Egawa (Author), Yoshihisa Kitamura (Author), Nobuaki Egashira (Author), Katsunori Iwasaki (Author), Michihiro Fujiwara (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In order to determine the differential effects of flavonoids on cerebral ischemia, we investigated the effects of (−)-epigallocatechin gallate (EGCG), catechin, rutin, and quercetin on spatial memory impairment and neuronal death induced by repeated cerebral ischemia in rats. Both rutin and querceti...