Constant Voltage Iontophoresis Technique to Deliver Terbinafine via Transungual Delivery System: Formulation Optimization Using Box-Behnken Design and In Vitro Evaluation

• Main Authors: Anroop B. Nair (Author), Bandar E. Al-Dhubiab (Author), Jigar Shah (Author), Bapi Gorain (Author), Shery Jacob (Author), Mahesh Attimarad (Author), Nagaraja Sreeharsha (Author), Katharigatta N. Venugopala (Author), Mohamed A. Morsy (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Topical therapy of antifungals is primarily restricted due to the low innate transport of drugs through the thick multi-layered keratinized nail plate. The objective of this investigation was to develop a gel formulation, and to optimize and evaluate the transungual delivery of terbinafine using the...