An In Vitro Model to Investigate the Potential of Solid Dispersions to Form Pharmacobezoars

An In Vitro Model to Investigate the Potential of Solid Dispersions to Form Pharmacobezoars

The formation of pharmacobezoars from suspensions of spray-dried amorphous solid dispersions (SD-ASDs) of new chemical entities (NCEs) and hydroxypropyl methylcellulose acetate succinate (HPMC-AS) represents a non-compound related adverse effect in preclinical oral toxicity studies in rodents. Where...

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Main Authors: Hannes Gierke (Author), Kerstin Schaefer (Author), Lukas Gerlich (Author), Ann-Cathrin Willmann (Author), Verena Bialetzki (Author), Georg Boeck (Author), Teresa Pfrommer (Author), Thomas Nolte (Author), Werner Weitschies (Author)
Format: Book
Published: MDPI AG, 2022-11-01T00:00:00Z.
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