Inhibition of the skeletal muscle Lands cycle ameliorates weakness induced by physical inactivity

• Autors principals: Justin L. Shahtout (Autor), Hiroaki Eshima (Autor), Patrick J. Ferrara (Autor), J. Alan Maschek (Autor), James E. Cox (Autor), Micah J. Drummond (Autor), Katsuhiko Funai (Autor)
• Format: Llibre
• Publicat: Wiley, 2024-02-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background Lipid hydroperoxides (LOOH) have been implicated in skeletal muscle atrophy with age and disuse. Lysophosphatidylcholine acyltransferase 3 (LPCAT3), an enzyme of the Lands cycle, conjugates a polyunsaturated fatty acyl chain to a lysophospholipid to form a polyunsaturated fatty a...