Inhibition of the skeletal muscle Lands cycle ameliorates weakness induced by physical inactivity

Abstract Background Lipid hydroperoxides (LOOH) have been implicated in skeletal muscle atrophy with age and disuse. Lysophosphatidylcholine acyltransferase 3 (LPCAT3), an enzyme of the Lands cycle, conjugates a polyunsaturated fatty acyl chain to a lysophospholipid to form a polyunsaturated fatty a...

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Main Authors: Justin L. Shahtout (Author), Hiroaki Eshima (Author), Patrick J. Ferrara (Author), J. Alan Maschek (Author), James E. Cox (Author), Micah J. Drummond (Author), Katsuhiko Funai (Author)
Formato: Livro
Publicado em: Wiley, 2024-02-01T00:00:00Z.
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