CVM-1118 (foslinanib), a 2-phenyl-4-quinolone derivative, promotes apoptosis and inhibits vasculogenic mimicry via targeting TRAP1

CVM-1118 (foslinanib), a 2-phenyl-4-quinolone derivative, promotes apoptosis and inhibits vasculogenic mimicry via targeting TRAP1

CVM-1118 (foslinanib) is a phosphoric ester compound selected from 2-phenyl-4-quinolone derivatives. The NCI 60 cancer panel screening showed CVM-1125, the major active metabolite of CVM-1118, to exhibit growth inhibitory and cytotoxic effects at nanomolar range. CVM-1118 possesses multiple bioactiv...

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Main Authors: Lifen Shen (Author), Yen-Ling Chen (Author), Chu-Chun Huang (Author), Yu-Chiau Shyu (Author), Richard E. B. Seftor (Author), Elisabeth A. Seftor (Author), Mary J. C. Hendrix (Author), Du-Shieng Chien (Author), Yi-Wen Chu (Author)
Format: Book
Published: Frontiers Media S.A., 2023-06-01T00:00:00Z.
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3rd Floor Main Library

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