The high frequency of spontaneous micronuclei observed in lymphocytes of systemic sclerosis patients: preliminary results

• Main Authors: G. Porciello (Author), R. Scarpato (Author), F. Storino (Author), F. Cagetti (Author), R. Marcolongo (Author), L. Migliore (Author), C. Ferri (Author), M. Galeazzi (Author)
• Format: Book
• Published: PAGEPress Publications, 2002-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: aim of the study is to assess the presence of spontaneous chromosome damage in patients affected by limited (lSSc) or diffuse (dSSc) Systemic Slerosis, using the micronucleus (MN) assay. Methods: we evaluated MN frequency in cultured peripheral lymphocytes of 18 SSc and in a group of 20 h...