The Influence of Pressure on the Intrinsic Dissolution Rate of Amorphous Indomethacin

• मुख्य लेखकों: Korbinian Löbmann (लेखक), Konstantina Flouda (लेखक), Danwen Qiu (लेखक), Theodosia Tsolakou (लेखक), Wenbo Wang (लेखक), Thomas Rades (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2014-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

New drug candidates increasingly tend to be poorly water soluble. One approach to increase their solubility is to convert the crystalline form of a drug into the amorphous form. Intrinsic dissolution testing is an efficient standard method to determine the intrinsic dissolution rate (IDR) of a drug...