DJ-1-Mediated Protective Effect of Protocatechuic Aldehyde Against Oxidative Stress in SH-SY5Y Cells

• Main Authors: Jian-Wei Gao (Author), Takuya Yamane (Author), Hiroshi Maita (Author), Shizuma Ishikawa (Author), Sanae M.M. Iguchi-Ariga (Author), Xiao-Ping Pu (Author), Hiroyoshi Ariga (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

DJ-1 was identified as a causal gene for a familial form of early onset Parkinson's disease (PD), park 7. DJ-1 plays roles in transcriptional regulation and the anti-oxidative stress reaction. In this study, we found that protocatechuic aldehyde (PAL), a traditional Chinese medicine compound, b...