Comprehensive analyses of PDHA1 that serves as a predictive biomarker for immunotherapy response in cancer

• Autors principals: Langmei Deng (Autor), Anqi Jiang (Autor), Hanqing Zeng (Autor), Xiaoji Peng (Autor), Liying Song (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Recent studies have proposed that pyruvate dehydrogenase E1 component subunit alpha (PDHA1), a cuproptosis-key gene, is crucial to the glucose metabolism reprogram of tumor cells. However, the functional roles and regulated mechanisms of PDHA1 in multiple cancers are largely unknown. The Cancer Geno...