Synthesis and evaluation of cationic polymeric micelles as carriers of lumbrokinase for targeted thrombolysis

To achieve targeted thrombolysis, a targeted delivery system of lumbrokinase (LK) was constructed using RGDfk-conjugated hybrid micelles. Based on the specific affinity of RGDfk to glycoprotein complex of GPⅡb/Ⅲa expressed on the surface of membrane of activated platelet, LK loaded targeted micelles...

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Hoofdauteurs: Yang Pan (Auteur), Xiahui Wang (Auteur), Zongning Yin (Auteur)
Formaat: Boek
Gepubliceerd in: Elsevier, 2019-03-01T00:00:00Z.
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