A Robust Nanoparticle Platform for RNA Interference in Macrophages to Suppress Tumor Cell Migration

• Main Authors: Shi Liang (Author), Junmeng Zheng (Author), Wei Wu (Author), Quan Li (Author), Phei Er Saw (Author), Jianing Chen (Author), Xiaoding Xu (Author), Herui Yao (Author), Yandan Yao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophages are one of the most abundant immune cells in the solid tumor and their increased density is associated with the specific pathological features of cancers, including invasiveness, metastasis, immunosuppression, neovascularization, and poor response to therapy. Therefore, reprogramming mac...