Overexpression of BIRC6 driven by EGF-JNK-HECTD1 signaling is a potential therapeutic target for triple-negative breast cancer

• Main Authors: Yongpeng Li (Author), Yanan Tan (Author), Lijuan Wen (Author), Zhihao Xing (Author), Changxu Wang (Author), Liuhui Zhang (Author), Kai Wu (Author), Haiyan Sun (Author), Yuqing Li (Author), Qifang Lei (Author), Song Wu (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Triple-negative breast cancer (TNBC) is an aggressive and highly lethal disease. The lack of targeted therapies and poor patient outcome have fostered efforts to discover new molecular targets to treat patients with TNBC. Here, we showed that baculoviral IAP repeat containing 6 (BIRC6) is overexpres...