An ImmunoSignature test distinguishes Trypanosoma cruzi, hepatitis B, hepatitis C and West Nile virus seropositivity among asymptomatic blood donors.

• Main Authors: Michael Rowe (Author), Jonathan Melnick (Author), Robert Gerwien (Author), Joseph B Legutki (Author), Jessica Pfeilsticker (Author), Theodore M Tarasow (Author), Kathryn F Sykes (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The complexity of the eukaryotic parasite Trypanosoma (T.) cruzi manifests in its highly dynamic genome, multi-host life cycle, progressive morphologies and immune-evasion mechanisms. Accurate determination of infection or Chagas' disease activity and prognosis continues to challenge researcher...