Adverse Effects of Methylglyoxal on Transcriptome and Metabolic Changes in Visceral Adipose Tissue in a Prediabetic Rat Model

• Главные авторы: Martina Hüttl (Автор), Irena Markova (Автор), Denisa Miklankova (Автор), Pavol Makovicky (Автор), Terezie Pelikanova (Автор), Ondrej Šeda (Автор), Lucie Šedová (Автор), Hana Malinska (Автор)
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• Опубликовано: MDPI AG, 2020-08-01T00:00:00Z.
• Предметы: article
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Excessive methylglyoxal (MG) production contributes to metabolic and vascular changes by increasing inflammatory processes, disturbing regulatory mechanisms and exacerbating tissue dysfunction. MG accumulation in adipocytes leads to structural and functional changes. We used transcriptome analysis t...