SPAG6 overexpression decreases the pro-apoptotic effect of daunorubicin in acute myeloid leukemia cells through the ROS/JNK MAPK axis in a GSTP1-dependent manner

• मुख्य लेखकों: Jie Luo (लेखक), Li Ding (लेखक), Shirui Pan (लेखक), Jing Luo (लेखक), Haiqiu Zhao (लेखक), Jiaxiu Yin (लेखक), Rong Su (लेखक), Jiamin Zhang (लेखक), Lin Liu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

IntroductionAs a malignant hematological disease, the incidence of acute myeloid leukemia (AML) has exhibited an upward trend in recent years. Nevertheless, certain limitations persist in the treatment of AML. Sperm-associated antigen 6 (SPAG6) has been implicated in the onset and progression of var...